Figure 6
Effect of carnosine in a mouse xenograft model. (A) Graph showing slower growth of tumors in the group treated with carnosine. Carnosine treatment began on the 14th day after subcutaneous implantation of HeLa cells, and tumor size was measured using a caliper during treatment. (B) There was a significant difference in the weight of tumors from treated and control groups (t-test, **p < 0.01). (C) Immunohistochemical staining of tumor tissue sections demonstrated enhanced expression of HIF-1α and CA IX proteins in the carnosine-treated group.