Figure 1

MMP-10 expression is high in cervical cancer tissue. Representative images of benign cervical tissue (A), cervical tumor with weak (B), and cervical tumor with strong (C) MMP-10 expression (brown). Representative image of a cervical tumor core on a tissue microarray (D), MMP-10 expression in the tumor-associated stroma (E), and in the tumor epithelia (F). Scale bars, 100 μm. G, quantification of MMP-10 expression levels in benign cervical tissue (n = 10) vs. cervical tumor (n = 70). Increased MMP-10 expression was noted in cervical tumors compared to benign cervical tissue. H, quantification of MMP-10 expression levels in low stage cervical tumors vs. high stage cervical tumors. Increased MMP-10 expression was noted in high stage cervical tumors.