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Table 5 Standardised incidence ratios of second primary cancer by time since diagnosis

From: Second primary cancer risk - the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study

   

Registry

IARC/IACR

SEER

Registry‡

First primary cancer

 

Time since diagnosis

SIR (95% CI)

SIR (95% CI)

SIR (95% CI)

SIR (95% CI)

Lung cancer (C33-34)

 

61 days- < 1 year

0.55

(0.39, 0.76)

0.47

(0.32, 0.66)

0.38

(0.27, 0.53)

0.58

(0.39, 0.82)

 

1-5 years

0.98

(0.78, 1.22)

0.88

(0.69, 1.11)

0.95

(0.75, 1.18)

1.04

(0.81, 1.32)

Colorectal cancer (C18-20)

 

61 days- < 1 year

0.79

(0.61, 1.00)

0.73

(0.56, 0.94)

0.78

(0.60, 0.99)

0.81

(0.61, 1.04)

 

1-5 years

0.93

(0.82, 1.05)

0.86

(0.75, 0.98)

0.93

(0.82, 1.05)

0.88

(0.77, 1.01)

Prostate cancer (C61)

 

61 days- < 1 year

0.77

(0.61, 0.96)

0.75

(0.59, 0.94)

0.75

(0.59, 0.94)

0.94

(0.74, 1.18)

 

1-5 years

0.69

(0.61, 0.78)

0.69

(0.61, 0.78)

0.69

(0.61, 0.78)

0.87

(0.77, 0.98)

Breast cancer (C50)

age < 50

61 days- < 1 year

1.05

(0.29, 2.70)

0.53

(0.06, 1.90)

0.79

(0.16, 2.31)

1.11

(0.23, 3.25)

 

1-5 years

2.32

(1.71, 3.07)

1.11

(0.70, 1.66)

2.22

(1.63, 2.96)

1.77

(1.15, 2.62)

Breast cancer (C50)

age ≥ 50

61 days- < 1 year

0.75

(0.56, 0.98)

0.65

(0.47, 0.87)

0.68

(0.50, 0.90)

0.84

(0.61, 1.13)

 

1-5 years

0.91

(0.80, 1.02)

0.70

(0.61, 0.81)

0.88

(0.77, 1.00)

1.16

(1.02, 1.32)

Head & neck (C00-C14, C30-C32)

 

61 days- < 1 year

1.33

(0.91, 1.88)

1.25

(0.84, 1.78)

1.29

(0.88, 1.83)

1.05

(0.67, 1.56)

 

1-5 years

2.10

(1.80, 2.44)

2.02

(1.73, 2.36)

2.07

(1.77, 2.41)

1.94

(1.64, 2.27)

  1. ‡excluding same site.
  2. Abbreviations: SEER Surveillance Epidemiology and End Results, IARC International Agency for Research on Cancer, IACR International Association of Cancer Registries, SIR standardised incidence ratio, CI confidence interval.