| Patients VEGFR TKI | Patient controls | Healthy controls | |||
---|---|---|---|---|---|---|
 | Mean | SD | Mean | SD | Mean | SD |
Learning & memory | Â | Â | Â | Â | Â | Â |
Working memory | -0.26 | 0.93 | 0.11 | 0.95 | 0.19 | 0.79 |
  Digit span backwards WAIS-III | 5.67 | 1.77 | 6.40 | 1.98 | 6.37 | 1.75 |
  Letter-number sequencing WAIS-III | 9.47 | 2.27 | 10.15 | 2.08 | 10.50 | 1.59 |
Episodic memory | -0.31*** | 0.89 | -0.11* | 0.74 | 0.38 | 0.56 |
  RAVLT total score | 33.70 | 8.01 | 37.55 | 8.25 | 39.77 | 5.76 |
  RAVLT delayed recall | 5.87 | 2.57 | 7.00 | 2.32 | 7.37 | 2.50 |
  RAVLT delayed recognition | 26.33 | 3.02 | 27.70 | 1.59 | 28.03 | 1.45 |
  RBMT story (Immediate Recall) | 9.62 | 2.75 | 9.42 | 3.14 | 11.75 | 2.51 |
  RBMT story (Delayed Recall) | 8.43 | 3.51 | 7.85 | 3.30 | 10.38 | 2.56 |
Semantic memory | -0.36*** | 0.97 | -0.26** | 0.89 | 0.53 | 0.88 |
  Semantic fluency (Animal) | 22.47 | 5.49 | 22.95 | 4.39 | 26.73 | 5.22 |
  Semantic fluency (Profession) | 16.30 | 4.65 | 16.80 | 5.19 | 20.70 | 4.21 |
Attention & concentration | Â | Â | Â | Â | Â | Â |
Alertness | -0.17 | 0.88 | 0.17 | 0.68 | 0.06 | 0.59 |
  Digit span forwards WAIS-III | 8.23 | 2.05 | 9.20 | 1.94 | 8.47 | 1.28 |
  TAP 2.1 alertnessa | 256.28 | 51.96 | 248.40 | 35.52 | 240.75 | 27.45 |
Sustained attention | -0.22 | 0.93 | 0.18 | 1.16 | 0.10 | 0.94 |
  d2 test | 138.63 | 30.93 | 151.60 | 38.33 | 149.03 | 31.25 |
Executive functions | Â | Â | Â | Â | Â | Â |
Response generation | -0.26* | 0.91 | -0.13 | 1.23 | 0.35 | 0.83 |
  Letter fluency (COWAT) | 32.97 | 9.28 | 34.25 | 12.58 | 39.17 | 8.46 |
Response inhibition | -0.04 | 1.05 | 0.01 | 1.05 | 0.04 | 0.95 |
  Stroop color word test (Interference)a | 0.70 | 0.30 | 0.73 | 0.47 | 0.65 | 0.21 |
Mental flexibility | -0.29 | 0.98 | 0.11 | 1.13 | 0.22 | 0.88 |
  TAP flexibility (Alternation)a | 900.37 | 353.23 | 824.40 | 405.37 | 732.03 | 177.52 |
Problem solving | -0.19* | 0.88 | -0.18* | 0.85 | 0.31 | 0.74 |
  Raven APM (Set I) | 8.00 | 2.23 | 8.10 | 2.02 | 9.50 | 1.93 |
  Brixton spatial anticipation Test | 36.97 | 6.06 | 36.90 | 6.31 | 38.83 | 5.43 |