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Figure 1 | BMC Cancer

Figure 1

From: Loss of the NKX3.1 tumorsuppressor promotes the TMPRSS2-ERG fusion gene expression in prostate cancer

Figure 1

Defining a conserved composite model for NKX3.1 binding within the TMPRSS2 gene promoter upstream sequences. (A) Frequency of TMPRSS2-ERG transcript initiation sites within the TMPRSS2 promoter transcriptional start region (TSR). (B) NKX3.1 model match within the human TMPRSS2 promoter upstream region with conserved distance, positions and orientations (arrows) of transcription factor binding sites.

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BMC Cancer

ISSN: 1471-2407

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