Figure 1From: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer MK-2206 inhibits Akt signaling in IGF1R-dependent CRC cells. A) & B) Loss of pAkt at Ser473 and T308 on treatment with increasing concentration of MK-2206 for 72 hours in GEO and CBS cells respectively. GAPDH is used as a loading control.Back to article page