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Figure 2 | BMC Cancer

Figure 2

From: Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response

Figure 2

YAP1 mRNA predicts outcome in molecular subgroups of primary breast cancer. (a) YAP1 mRNA expression was dichotomised at the median value to generate high and low YAP1 expressing groups. Low YAP1 mRNA correlates to a decreased recurrence-free survival in the entire dataset. (b) YAP1 mRNA quartiles of the ER+ subgroup (n = 700) correlates to a decreased recurrence-free survival whereas the trend in the (c) ER- subgroup (n = 239) is opposite but not significant. (d-h) Survival analyses in breast cancer molecular subgroups. Low YAP1 mRNA is associated with decreased recurrence-free survival in the luminal A but not luminal B, HER2, basal or normal-like subgroups. Q = quartile, RFS = recurrence-free survival.

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BMC Cancer

ISSN: 1471-2407

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