|
CXCR3
|
CXCR4
|
CXCR7
|
CCR7
|
CCR10
|
---|
|
%
|
MFI
|
%
|
MFI
|
%
|
MFI
|
%
|
MFI
|
%
|
MFI
|
---|
WM-115 | 88.59 | 5.40 | 92.45 | 3.95 | 4.97 | 1.57 | 20.16 | 1.70 | 13.67 | 1.57 |
WM-115-X | 59.84 | 3.46 | 14.10 | 1.62 | 58.89 | 4.14 | 75.32 | 4.10 | 66.90 | 3.47 |
WM-115-CX | 76.11 | 3.95 | 12.14 | 1.65 | 5.44 | 1.34 | 82.03 | 3.44 | 81.90 | 3.44 |
WM-266 | 74.08 | 2.22 | 96.26 | 3.39 | 21.53 | 1.68 | 40.16 | 1.69 | 24.00 | 1.63 |
WM-266-X | 28.19 | 2.24 | 6.71 | 1.26 | 13.96 | 2.08 | 56.31 | 2.50 | 28.54 | 1.83 |
WM-266-CX | 91.65 | 4.41 | 94.17 | 3.74 | 53.67 | 2.34 | 72.95 | 2.48 | 88.62 | 4.60 |
- Mean percentage (%) and Mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of samples stained with the mAb anti-receptor and correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors intracellularly. WM-115 and WM-266 represent the mean values of the original cell lines; WM-115-X and WM-266-X represent the mean values of the different xenografts; WM-115-CX and WM-266-CX represent the mean values of the different cell lines obtained after culturing the xenografts.