Figure 2

Resistin-induced SK-Hep1 cell adhesions to HUVECs were inhibited by AMPK. (A) SK-Hep1 cells were pretreated with AICAR, AMPK activator, at different concentrations (i.e. 0, 0.1, 0.5 and 1 ng/ml) for 1 h. They were then kept as the control (CL) or treated with resistin (50 ng/mL) for 4 h. (B) SK-Hep1 cells were pretreated with AICAR at 0 or 1 ng/mL for 1 h. They were then kept as the control (CL) or treated with different concentrations of resistin (i.e. 10, 25 and 50 ng/mL) for 4 h. The bar graphs represent the mean ± SEM from three independent experiments. *, P < 0.05 vs. control cells. #, P < 0.05 vs. cells treated with resistin only.