Variable | Test set | |||
---|---|---|---|---|
Patients | N | 16 | ||
Age | Median | 60.6 | ||
Range | 24-71 | |||
N (%) | ||||
Best response | CR | 3 (18.8%) | ||
PR | 9 (56.2%) | |||
SD | 2 (12.6%) | |||
PD | 2 (12.6%) | |||
Histological Grade | 1-2 | 10 (62.6%) | ||
3-4 | 5 (31.2%) | |||
Gender | Female | 8 (50%) | ||
Male | 8 (50%) | |||
Progressive disease within 8 months | 6 (37.6%) | |||
Microarray analysis: Gene selection | ||||
Gene | Name | EntrezID | Fold change in 8-month Progression-free cohort | FDR |
KLF12 | Kruppel-like factor 12 | 11278 | 1.87 | 0.092 |
AGR2 | Anterior gradient homolog 2 (Xenopus laevis) | 10551 | 0.62 | 0.092 |
ALDH6A1 | Aldehyde dehydrogenase 6 family, member A1 | 4329 | 0.63 | 0.092 |
MCM5 | Minichromosome maintenance complex component 5 | 4174 | 0.48 | 0.157 |
TFF2 | Trefoil factor 2 | 7032 | 0.45 | 0.002 |