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Table 4 Multivariate Cox regression analyses (stepwise procedure) on (a) general population and (b) population with available biological parameters

From: Comparative performances of prognostic indexes for breast cancer patients presenting with brain metastases

a)

HR

95% CI

P

RPA 2

2.76

1.64–4.66

<0.001

RPA 3

8.42

4.36–16.26

<0.001

Le Scodan 2

1.49

1.01–2.19

0.041

Le Scodan 3

1.87

1.30–2.69

0.001

GPA 3

1.75

1.22–2.51

0.002

b)

HR

95% CI

P

RPA 2

2.42

1.36–4.29

0.003

RPA 3

13.26

6.94–25.30

<0.001

Le Scodan 3

1.57

1.03–2.39

0.035

P1PS 2/3

2.23

1.54–3.24

<0.001

  1. RPA, recursive partitioning analysis, GPA, graded partitioning analysis, P1PS, phase 1 prognostic score, HR, hazard ratio, CI, confidence interval.