Table 2 Study population
Patient characteristics | Number of patients | % |
|---|---|---|
Age at breast cancer diagnosis (years) | ||
Median, range | 50 (23–82) | |
Age at BM diagnosis (years) | ||
Median, range | 55 (25–85) | |
Time between initial diagnosis and BM diagnosis (months) | ||
Median, range | 39.4 (0–319.2) | |
Hormone receptor status | ||
Positive | 119 | 47.6 |
Negative | 131 | 52.4 |
HER-2 status | ||
Positive | 109 | 43.6 |
Negative | 141 | 56.4 |
Karnofsky Performance status | ||
100 | 66 | 26.4 |
80–90 | 119 | 47.6 |
60–70 | 28 | 11.2 |
40–50 | 32 | 12.8 |
10-30 | 5 | 2 |
Extra-cerebral metastases at BM diagnosis | ||
Yes | 219 | 87.6 |
No | 31 | 12.4 |
Systemic treatment after BM diagnosis | ||
Chemotherapy | ||
Yes | 177 | 70.8 |
No | 73 | 29.2 |
Anti-HER2 treatment for HER2+ patients | ||
Yes | 20 | 18.3 |
No | 89 | 81.7 |