Comprehensive analyses of imprinted differentially methylated regions reveal epigenetic and genetic characteristics in hepatoblastoma

Table 1 Clinical information of hepatoblastoma cases

Case	Sex/age^a	Histology	PRETEXT	Preoperative chemotherapy^b	POSTTEXT	Outcome	Other information
HB01	F/1y3m	Combined fetal and embryonal type	III	CITA4	III	Alive
HB02	F/3y2m	Fetal type^c	III	CITA4	III	Aive
HB03	F/7y11m	Hepatoblastoma (NOS)^d	III	CITA5	III	Alive	Small for gestational age
HB04	M/1y4m	Mixed epithelial and mesenchymal with teratoid feature^c	IV	CITA4 + ITEC2	IV	Alive
HB05	M/1y2m	Mixed epithelial and mesenchymal with teratoid feature	III	CITA5	II	Alive
HB06	M/10m	Mixed epithelial and mesenchymal with teratoid feature	III	CITA4	III	Alive
HB07	M/8m	Combined fetal and embryonal type	II	CITA2	II	Alive
HB08	F/28d	Combined fetal and embryonal type	II			Alive
HB09	M/1y6m	Combined fetal and embryonal type	II			Treatment related death	Small for gestational age
HB10	F/6y6m	Fetal type	II	CITA2	II	Alive
HB11	F/3m	Combined fetal and embryonal type	IV	CITA7	III	Treatment related death
BWS109	F/1y0m	Hepatoblastoma (NOS)^d	IV,M(+)	CITA7 + ITEC1	IV	Alive	Beckwith-Wiedemann syndrome, liver transplantation at 1 year old

^aage at diagnosis, ^bCITA: cisplatin-pirarubicin, ITEC: Ifosfamide, pirarubicin, etoposide, and carboplatin. The numerals indicate the cycle numbers of the chemotherapy. ^cdifficult to diagnose due to chemotherapy, ^dnot otherwise specified.

ISSN: 1471-2407