Table 2 mRNA biomarkers and gene mutation status
Biomarkers and mutations | N (%) | Median RQ | Interquartile range (IQR) |
|---|---|---|---|
AREG | 168 | 39.9 | 38.7-40.9 |
EREG | 160 | 36.4 | 34.7-37.9 |
EGF | 167 | 29.3 | 27.9-33.6 |
TGFa | 162 | 37.1 | 36.2-37.9 |
EGFR | 168 | 38.3 | 37.7-39.2 |
KRAS N=205 | |||
All mutations | 72 (31.9%) | ||
G12 | 45 (20.0%) | ||
G13 | 16 (7.0%) | ||
Q61 | 4 (1.7%) | ||
A146 | 7 (3.1%) | ||
Wild type | 133 (58.8%) | ||
Missing | 21 (9.3%) | ||
NRAS N=159 | |||
All mutations | 7 (3.1%) | ||
Q61 | 5 (2.2%) | ||
G12 | 2 (0.9%) | ||
Wild type | 152 (67.3%) | ||
Missing | 67 (29.6%) | ||
BRAF N=220 | |||
V600E | 6 (2.6%) | ||
Wild type | 214 (94.7%) | ||
Missing | 6 (2.6%) | ||
PIK3CA N=220 | |||
All mutations | 37 (16.4%) | ||
Exon 9 | 20 (8.8%) | ||
Exon 20 | 5 (2.2%) | ||
Other | 12 (5.3%) | ||
Wild type | 183 (81.0%) | ||
Missing | 6 (2.6%) |