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Table 4 Body composition measures and breast cancer

From: Body fatness and breast cancer risk in women of African ancestry

 

Pre-menopausal

Post-menopausal

 

Cases/Controls

OR1

95% CI

OR2

95% CI

Cases/Controls

OR1

95% CI

OR2

95% CI

Fat mass (kg)

          

  ≤25.3

128/125

Ref

 

Ref

 

101/102

Ref

 

Ref

 

 25.4–34.1

131/116

1.08

0.74–1.56

1.24

0.82–1.87

126/107

1.16

0.78–1.74

1.34

0.86–2.07

 34.2–44.3

96/100

0.92

0.62–1.37

1.19

0.70–2.03

124/123

0.94

0.63–1.40

1.21

0.72–2.04

 >44.3

87/114

0.82

0.54–1.23

1.39

0.61–3.14

120/110

1.05

0.70–1.57

1.69

0.82–3.49

  p for trend

  

0.24

 

0.49

  

0.93

 

0.22

Fat free mass (kg)

          

 ≤44.1

112/108

Ref

 

Ref

 

130/118

Ref

 

Ref

 

 44.2–48

121/125

0.94

0.64–1.39

1.04

0.70–1.55

134/99

1.28

0.87–1.88

1.32

0.88–1.96

 48.1–52.6

106/99

1.00

0.67–1.51

1.24

0.78–1.98

107/124

0.87

0.59–1.27

0.92

0.59–1.43

 >52.6

103/123

0.84

0.57–1.26

1.32

0.70–2.47

101/101

0.96

0.65–1.43

1.05

0.61–1.83

  p for trend

  

0.44

 

0.35

  

0.47

 

0.88

Percent body fat

          

 ≤35.9

145/137

Ref

 

Ref

 

93/94

Ref

 

Ref

 

 36–41.6

118/118

0.92

0.64–1.33

1.02

0.69–1.52

123/107

1.14

0.75–1.71

1.27

0.83–1.96

 41.7–46.5

96/104

0.88

0.60–1.30

1.07

0.67–1.72

119/124

0.85

0.57–1.29

1.05

0.65–1.70

 >46.5

83/106

0.82

0.55–1.23

1.22

0.62–2.42

137/119

1.09

0.73–1.63

1.59

0.87–2.93

  p for trend

  

0.32

 

0.65

  

0.98

 

0.26

Fat mass index

          

 ≤9.37

128/129

Ref

 

–

–

86/96

Ref

 

-

-

 9.38–12.78

138/119

1.09

0.75–1.58

-

-

124/104

1.39

0.92–2.11

-

-

 12.79–16.77

93/98

0.95

0.63–1.42

-

-

140/127

1.13

0.75–1.70

-

-

 >16.77

83/109

0.80

0.53–1.21

-

-

121/115

1.10

0.72–1.66

-

-

  p for trend

  

0.35

-

-

  

0.58

-

-

Fat free mass index

   

-

-

   

-

-

 ≤16.64

126/118

Ref

 

-

-

123/106

Ref

 

-

-

 16.65-18.04

116/121

0.88

0.60–1.28

-

-

108/104

0.94

0.63–1.40

-

-

 18.05–19.80

99/99

0.85

0.57–1.28

-

-

129/124

0.89

0.60–1.30

-

-

 >19.80

101/117

0.81

0.54–1.21

-

-

112/108

0.86

0.58–1.28

-

-

  p for trend

  

0.33

-

-

  

0.45

-

-

  1. Fat mass index: fat mass in kg/(height in m)2; Fat Free Mass index: fat free mass in kg/(height in m)2 OR1: Adjusted for age, ethnicity, country of origin, education, family history of breast cancer, history of benign breast disease, age at menarche, years since menopause (for postmenopausal women), parity (continuous), breastfeeding (yes/no), age at first birth, HRT use (never/ever), OC use (never/ever). OR2: Further adjusted for BMI.
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BMC Cancer

ISSN: 1471-2407

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