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Table 3 The association of GGH, FAAH, PIR and TAF5L to the clinicopathological characteristics in addition to clinical outcomes

From: High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer

Characteristics

FAAH

PIR

TAF5L

GGH

Negative

Positive

Negative

Positive

Negative

Positive

Negative

Positive

8 (100)

64 (100)

11 (100)

61 (100)

40 (100)

32 (100)

18 (100)

56 (100)

Survival ≥8 yrs

4 (12)

29 (88)

4 (12)

29 (88)

18 (55)

15 (45)

11 (36)

22 (64)

Survival <8 yrs

4 (10)

35 (90)

7 (18)

32 (82)

22 (57)

17 (43)

5 (16)

34 (84)

 

P = 0.55

 

P = 0.53

 

P = 1

 

P = 0.037

 

Recurrence

        

No

3 (12)

22 (88)

2 (8)

23 (92)

16 (64)

9 (36)

9 (36)

16 (64)

Yes

0 (0)

18 (100)

2 (11)

16 (89)

7 (39)

11 (61)

0 (0)

18 (100)

 

P = 0.29

 

P = 0.87

 

P = 0.12

 

P = 0.009

 

Age

        

27-59

2 (9)

20 (91)

3 (14)

19.(86)

12 (55)

10 (45)

6 (27)

16 (73)

≥60

16 (73)

44 (88)

8 (16)

42 (84)

28 (56)

22 (44)

12 (24)

38 (76)

 

P = 0.54

 

P = 1

 

P = 1

 

P = 0.78

 

BRE grade

        

I-II

5 (14)

31 (86)

4 (11)

32 (89)

16 (44)

20 (66)

15 (42)

21 (58)

III

3 (8)

33 (92)

7 (19)

29 ( 81)

24 (67)

12 (33)

3 (8)

33 (92)

 

P = 0.71

 

P = 0.51

 

P = 0.06

 

P <0.001

 

Axillary lymph node status

        

Negative

2 (8)

22 (92)

7 (29)

17 (71)

14 (58)

10 (42)

5 (21)

19 (79)

Positive

6 (13)

42 (87)

4 (8)

44 (92)

26 (54)

22 (46)

13 (27)

35 (73)

 

P = 0.71

 

P = 0.034

 

P = 0.81

 

P = 0.88

 

No. of axillary lymph nodes

        

1-3

0 (0)

23 (100)

1 (4)

22 (96)

13 (43)

17 (57)

6 (26)

17 (74)

≥4

6 (24)

19 (76)

3 (12)

22 (88)

10 (56)

8 (44)

7 (28)

18 (72)

 

P = 0.023

 

P = 0.6

 

P = 0.56

 

P = 0.63

 

ER/PR status

        

Negative

5 (15)

29 (85)

4 (12)

30 (88)

19 (56)

15 (44)

10 (41)

27 (59)

Positive

3 (8)

35 (92)

7 (18)

31.(82)

21 (55)

17 (45)

4 (10)

34 (90)

 

P = 0.46

 

P = 0.52

 

P = 0.26

 

P = 0.01

 

HER2/ neu status

        

Negative

5 (14)

32 (86)

7 (19)

30 (81)

20 (54)

17 (46)

10 (71)

4 (29)

Positive

1 (5)

21 (95)

2 (9)

20 (91)

13 (59)

9 (41)

27 (60)

18 (40)

 

P = 0.4

 

P = 0.46

 

P = 0.79

 

P = 0.53

 

FAAH

        

Negative

  

2 (18)

9 (82)

4 (50)

4 (50)

5 (28)

13 (72)

Positive

  

6 (10)

55 (90)

36 (56)

28 (44)

3 (6)

51 (94)

 

-

 

P = 0.6

 

P = 1

 

P = 0.02

 

PIR

        

Negative

2 (25)

6 (75)

  

7 (64)

4 (36)

2 (11)

16 (89)

Positive

9 (14)

55 (86)

  

33 (54)

28 (46)

9 (17)

45 (83)

 

P = 0.6

 

-

 

P = 0.74

 

P = 0.72

 

TAF5L

        

Negative

4 (10)

36 (90)

3 (27)

8 (73)

  

5 (28)

13 (72)

Positive

4 (13)

28 (87)

13 (21)

48 (79)

  

11 (20)

43 (80)

 

P = 1

 

P = 0.7

 

-

 

P = 0.53

 

GGH

        

Negative

5 (63)

3 (37)

2 (18)

9 (82)

8 (44)

10 (66)

  

Positive

13 (20)

51 (80)

16 (26)

45 (74)

32 (59)

22 (41)

  
 

P = 0.02

 

P = 0.72

 

P = 0.53

 

-