Table 2 Distribution of genotypes and serum levels of vascular endothelial growth factor
Genotype | Polymorphism | No. of patients | % | Mean ± SD (pg/ml) | P* |
|---|---|---|---|---|---|
−2578C/A | CC | 116 | 61.1 | 453.2 ± 278.8 | 0.606 |
CA | 63 | 33.2 | 520.0 ± 392.3 | ||
AA | 11 | 5.8 | 523.9 ± 391.7 | ||
−2489C/T | CC | 116 | 61.1 | 453.2 ± 278.8 | 0.117 |
CT | 60 | 31.6 | 478.4 ± 350.0 | ||
TT | 14 | 7.4 | 724.0 ± 517.7 | ||
−1498 T/C | TT | 116 | 61.1 | 453.2 ± 278.8 | 0.563 |
TC | 61 | 32.1 | 512.2 ± 400.7 | ||
CC | 13 | 6.8 | 568.2 ± 324.9 | ||
−634 G/C | GG | 54 | 28.4 | 889.7 ± 453.7 | 0.004 |
GC | 93 | 48.9 | 471.4 ± 222.6 | ||
CC | 43 | 22.6 | 410.7 ± 222.6 | ||
+936C/T | CC | 135 | 71.1 | 440.0 ± 292.0 | 0.722 |
CT | 45 | 23.7 | 495.5 ± 329.3 | ||
TT | 10 | 5.3 | 502.6 ± 371.1 | ||
+1612 G/A | GG | 139 | 73.2 | 472.4 ± 339.2 | 0.371 |
GA | 47 | 24.7 | 538.3 ± 295.9 | ||
AA | 4 | 2.1 | 267.0 ± 159.3 |