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Figure 9 | BMC Cancer

Figure 9

From: Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice

Figure 9

Analysis of microarray data from SK-BR-3 cell line for interaction of maspin up- and down-stream mediators. The microarray data from SK-BR-3 cell treatment with DHA, CCM, and DHA + CCM was used to determine the interaction of maspin with up- and down-regulatory mediators using MetaCoreTM version 6.3 (GeneGo). The interactions indicate maspin is regulated upstream by p53, whereas maspin is linked to activation of a number of caspase activities downstream for its prominent role in the induction of apoptosis.

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BMC Cancer

ISSN: 1471-2407

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