Table 2 Comparison of thyroid function in breast cancer patients between prechemotherapy and postchemotherapy (mean ± SD)

T₃ (ng/ml)

1.16±0.27

0.80±0.27

<0.001

T₄ (μg/dl)

7.30±1.23

6.87±1.57

<0.001

FT₃ (pg/ml)

2.89±0.57

2.10±0.49

<0.001

FT₄ (ng/dl)

0.85±0.14

0.90±0.19

0.019

TSH (μIU/ml)

2.78±2.16

1.00±1.31

<0.001

Age (y)

49.8

Clinicopathological features

Number

Tumor size

T0 (impalpable)

7

T1 (≤2 cm)

66

T2 (>2 cm, ≤5 cm)

90

T3 (>5 cm)

12

Unknown

5

Tumor grade

I

8

II

150

III

13

Unknown

9

Clinical stage

0

9

I

46

II

107

III

7

IV

5

Unknown

6

Chemotherapy regimens

TEC

158

CEF

13

NP

8

Unknown

1