Figure 4
Effect of AG1478 or/and AG1024 plus irradiation on cell cycle in MDA-MB-468 cells. MDA-MB-468 cells were exposed to AG1478 10 μM, AG1024 10 μM and their combination plus irradiation at dose of 4 Gy for 48 h. Cell distribution in G0/G1 (a), S (b), G2/M (c) phase. Data represent mean values from three independent experiments. Columns, mean from three repeated experiments; bars, SD. (One-way ANOVAG0/G1 F = 71.498, p < 0.001; One-way ANOVAS, F = 6.897, p = 0.006; One-way ANOVAG2/M, F = 12.389, p = 0.001) ** p < 0.05, AG1478 + AG1024 + RT group vs. other treated groups. RT = radiotherapy.