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Table 1 Human breast cancer values for doubling time

From: Detection of cancer before distant metastasis

  

Tumor

Doubling time (months)

Publication

N

size (mm)

Median

Range

Lundgren 1977 [27]

13

N/A

6.9

1.4 – 13.0 a

Heuser 1979 [28]

32

14

10.6 b

3.6 – 31.0 a

Von Fournier 1980 [29]

100

17

6.6 b

2.1 – 20.6 c

Galante 1981 [30]

196

N/A

2.0

N/A

Tabbane 1989 [31]

75

N/A

3.8

0.5 – 25.3 a

Kuroishi 1990 [32]

142

N/A

5.7 b

0.4 – 42.4 a

Spratt 1993 [19]

448

9

8.5

5.0 – 15.7 d

Peer 1993 [33]

236

>10

5.0

1.5 – 17.1 e

Tilanus-Linthorst 2005 [34]

47

12

2.0 b

0.4 – 18.6 a

Weedon-Felkjaer 2008 [35]

969

15

3.1

1.0 – 9.6 d

Millet 2011 [36]

37

9

11.2 b

−222.9 – 146.6 a

  1. N/A: not available, a minimum-maximum, b mean, c 2.5-97.5 percentile, d 25-75 percentile, e 68% confidence interval.