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Table 3 Adverse Events of toremifene 120 mg and exemestane 25 mg in 88 treated patients

From: Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer

 

TOR120 (n = 43)

EXE (n = 45)

Grade1,2

Grade3,4

Grade1,2

Grade3,4

Nausea

4*

0

1

0

Fatigue

3*

0

1

0

Hot flush

3*

-

1

-

Night sweating

3*

-

0

-

Vaginal bleeding, discharge

2

-

0

-

Joint pain, disorder

1

-

2

-

Liver dysfunction

1

0

1

0

Exanthema

1

0

0

0

  1. * Three of 43 women treated with toremifene 120 mg were withdrawn from the trial in a few days because of early nausea, fatigue, hot flush and night sweating, which were appeared in same 3 patients.
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BMC Cancer

ISSN: 1471-2407

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