Table 4 Risk of glioma associated with genotypes by smoking status
From: Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility
Genotype | Smoking | Cases, n(%) | Controls, n(%) | OR (95% CI)a | P interaction b |
|---|---|---|---|---|---|
LIG4: rs1805388 | Â | Â | Â | Â | Â |
CC | No | 107 (27.9) | 122 (31.8) | 1.00 | 0.013/0.046 |
CT/TT | No | 121 (31.5) | 96 (25.0) | 1.39 (0.96-2.01) | Â |
CC | Yes | 56 (14.6) | 100 (26.0) | 0.62 (0.41-0.94) | Â |
CT/TT | Yes | 100 (26.0) | 66 (17.2) | 1.67 (1.11-2.50) | Â |
XRCC4: rs1805377 | Â | Â | Â | Â | Â |
AA | No | 120 (31.2) | 117 (30.5) | 1.00 | 0.536/0.886 |
AG/GG | No | 108 (28.1) | 101 (26.3) | 0.99 (0.68-1.44) | Â |
AA | Yes | 59 (15.4) | 78 (20.3) | 0.70 (0.46-1.07) | Â |
AG/GG | Yes | 97 (25.3) | 88 (22.9) | 1.02 (0.69-1.50) | Â |