Figure 7
Overexpression of BCL-2 prevents cisplatin mediated PTEN degradation in A2780 cells. A2780 cells were transfected with 2ug Bcl-2 plasmid or empty vector. After 48h of transfection, cells were treated with cisplatin and proteins were analyses by western blotting and GAPDH was used as loading control. Graphs show densitometric analysis of PTEN and BCL-2 in various groups. * p < 0.05 compared to vehicle treated cells, # p < 0.05 compared to empty vector transfected cells in the presence of cisplatin.