Figure 2

Uptake of ⁶⁴ Cu-ATSM within a maxillary squamous cell carcinoma. PET signalis presented in three planes of imaging; sagittal plane image on the left, dorsal plane image in the middle, and transverse plane on the right. A similar area of transection through the head in each plane was chosen between two time points, using anatomic landmarks of the orbit, mandibular rami, and medial canthus of the palpebrae. 2A represents the mass before treatment with toceranib, 2B 7 days post treatment. In 2A, the mass is best seen as a large area of ATSM uptake on dorsal plane PET image (white outline). Note the region of decreased uptake within the ventromedial portion of the mass, represented by the red dot on dorsal plane PET image, yellow dot on sagittal plane PET image, and green dot on transverse plane PET image.