Skip to main content

Table 1 Surface expression of IGF-1R and EGFR as determined by flow cytometry

From: Targeting both IGF-1R and mTOR synergistically inhibits growth of renal cell carcinoma in vitro

Antibody

Median fluorescence (%Positive)

 

Caki-2

ACHN

CAL-54

786-O

Caki-1

769-P

A-704

A-498

FITC GAH

3 (2)

3 (2)

5 (5)

4 (6)

4 (4)

3 (4)

7 (2)

3 (4)

hA20*

3 (2)

3 (2)

4 (6)

4 (6)

4 (4)

3 (4)

7 (2)

3 (4)

hR1

13 (70)

12 (52)

10 (36)

9 (71)

8 (21)

8 (21)

10 (5)

5 (21)

h225**

26 (95)

109 (99)

93 (99)

73 (98)

22 (76)

79 (98)

97 (92)

100 (98)

  1. *Humanized anti-CD20 antibody, veltuzumab.
  2. **Humanized anti-EGFR antibody.