Table 1 Relationship between change in mtDNA copy number and clinicopathological parameters
From: Association of decreased mitochondrial DNA content with the progression of colorectal cancer
Clinico-pathological parameter | Group | Number (n) | Low mtDNA copy number (n) | High mtDNA copy number (n) | Χ 2 and Z | P |
|---|---|---|---|---|---|---|
Sex | Male | 30 | 17 | 12 | 1.669 | 0.196 |
Female | 30 | 13 | 18 | |||
Age (years) | <57 | 30 | 16 | 13 | 0.601 | 0.438 |
≥57 | 30 | 14 | 17 | |||
Pathological stage | Well differentiated | 17 | 5 | 7 | −1.321 | 0.186 |
Moderately differentiated | 31 | 14 | 17 | |||
Poorly differentiated | 12 | 11 | 6 | |||
Lymph node metastasis | Positive | 17 | 12 | 5 | 4.022 | 0.045* |
Negative | 43 | 18 | 25 | |||
TNM stage | I | 6 | 2 | 4 | −1.604 | 0.109 |
II | 32 | 14 | 18 | |||
III | 14 | 9 | 5 | |||
IV | 8 | 5 | 3 |