Table 4 Patient self -evaluation of nausea and vomiting during the 1 st CT cycle (ITT population)
Placebo n = 217 | Cocculine n = 214 | All patients n = 431 | p | |
|---|---|---|---|---|
Nausea frequency | 0.59† | |||
missing data | 16 | 19 | 35 | |
number of patients evaluable | 201 | 195 | 396 | |
Number of patients with at least 1 episode of nausea, n (%) | 164 (81.6) | 155 (79.5) | 319 (80.6) | |
Nausea severity | 0.61* | |||
missing data | 16 | 19 | 35 | |
number of patients evalubale | 201 | 195 | 396 | |
Median (min-max) | 0.56 (0–8.5) | 0.58 (0–8.3) | 0.56 (0–8.5) | |
Vomiting frequency | 0.56† | |||
missing data | 31 | 19 | 50 | |
number of patients evaluable | 186 | 170 | 356 | |
Number of patients with at least 1 episode of vomiting, n (%) | 51 (27.4) | 42 (24.7) | 93 (26.1) | |
Vomiting severity | ||||
missing data | 22 | 25 | 47 | 0.44* |
number of patients evaluable | 195 | 189 | 384 | |
Median (min-max) | 0.00 (0–7.60) | 0.00 (0–5.0) | 0.00 (0–7.60) | |