From: Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma
Dose level (mg)
n
Dose limiting toxicity (n)
300
6
nausea, anorexia (1)
400
3
-
500
600
11
700
2
gastric perforation (2)