Table 1 Clinical and pathological characteristics of the Hodgkin lymphoma patients studied for GLUT1 and LDHA expression
HL cases | Membrane bound GLUT1 expression | Cytoplasmic LDHA expression | |
|---|---|---|---|
N | 207 | 102/207 (49%) | 68/153 (44%) |
Age, median in years | 34 | ||
Gender, male (%) | 48 | ||
Histology | |||
-Nodular sclerosis | 140 | 79/140 (56%) | 44/97 (45%) |
-Mixed cellularity | 29 | 12/29 (41%) | 8/22 (36%) |
-Lymphocyte-rich | 10 | 3/10 (30%) | 3/10 (30%) |
-Lymphocyte-depleted | 6 | 6/6 (100%) | 4/6 (67%) |
-NOS (not classifiable) | 9 | 0/9 (0%) | 3/5 (60%) |
-Lymphocyte predominant | 13 | 2/13 (15%) | 6/13 (46%) |
Stage (%) | |||
- I | 2 | ||
- II | 89 | ||
- III | 37 | ||
- IV | 25 | ||
B-Symptoms (%) | 46 | ||
Bulky disease (%) | 32 | ||
Interim-PET positive (%) | 18 | ||
Treatment | |||
- ABVD (%) | 80 | ||
- ABVD + radiation (%) | 20 |