Table 3 Univariate and multivariate analysis of overall survival by Cox model in gastric cancer

Sex: female vs male

0.896

0.728-1.103

0.302

Age, years: ≤40 vs ≤50 vs ≤65 vs >65

1.262

1.127-1.412

<0.001

1.226

1.089-1.379

0.001

Tumor site: upper vs middle vs lower vs diffuse†

0.998

0.883-1.128

0.976

Tumor size, cm: ≤2 vs ≤3 vs ≤5 vs >5

1.590

1.434-1.764

<0.001

1.149

1.023-1.291

0.019

Tumor grade: well vs moderate vs poor

1.540

1.287-1.841

<0.001

1.191

0.959-1.481

0.114

Lauren type: intestinal vs diffuse vs mixed

1.202

1.020-1.415

0.028

1.143

0.945-1.383

0.167

T classification: pT1 vs pT2 vs pT3 vs pT4‡

2.135

1.859-2.451

<0.001

1.490

1.263-1.757

<0.001

N classification: pN0 vs pN1 vs pN2 vs pN3‡

2.237

2.017-2.481

<0.001

1.733

1.543-1.947

<0.001

Radical resection: yes vs no

3.337

2.706-4.114

<0.001

2.053

1.641-2.570

<0.001

TNM stage: I vs II vs III vs IV‡§

2.306

2.064-2.576

<0.001

ERα: positive vs negative

1.990

1.380-2.871

<0.001

1.159

0.797-1.685

0.441

ERβ: positive vs negative

1.107

0.779-1.573

0.572

PR: positive vs negative

0.905

0.723-1.135

0.389

AR: positive vs negative

1.265

1.023-1.564

0.030

1.072

0.858-1.340

0.541