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Table 1 Clinicopathological characteristics of node negative breast cancer patients (fresh frozen tissue) from the Mainz cohort (n=200)

From: Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

Characteristics

n

%

Age at diagnosis

  

<50

49

24.5

≥50

151

75.5

pT stage

  

≤2cm

106

53.0

>2cm

88

44.0

not documented

6

3.0

Histological grade

  

G I

42

21.0

G II

109

54.5

G III

49

24.5

Estrogen receptor status1

  

RNA expression low

31

15.5

RNA expression high

169

84.5

Progesterone receptor status1

  

RNA expression low

  

RNA expression high

86

43.0

 

114

57.0

Hormone receptor status2

  

RNA expression low

  

RNA expression high

31

15.5

 

169

84.5

HER2 status1

  

RNA expression low

181

90.5

RNA expression high

19

9.5

Metastasis

  

Yes

47

23.5

No

153

76.5

  1. 1Estrogen, progesterone and HER2 status were derived from RNA levels as described in Schmidt et al., 2010 [34]. 2The hormone receptor status is defined as positive when one of either the estrogen or the progesterone receptor status is positive.