Figure 3
From: The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition
Mcl-1 and USP9X are co-overexpressed in colon and lung cancers. (a) Lung adenocarcinoma tissue slides were stained for USP9X and Mcl-1 proteins. (b) On slides containing colon adenocarcinoma tissue samples, USP9X and Mcl-1 staining was performed. (c) Pearson correlation between the USP9X and Mcl-1 expression data for 94 lung adenocarcinoma samples was calculated using R statistical software. (d) Pearson correlation between USP9X and Mcl-1 expression in 79 colon adenocarcinoma samples was determined using R statistical software. (e) The correlation between USP9X expressions and the clinical staging of different colon cancer samples was determined using linear regression. The mean levels within each stage, plus or minus one standard error, were plotted.