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Figure 1 | BMC Cancer

Figure 1

From: Immunohistochemical analysis based Ep-ICD subcellular localization index (ESLI) is a novel marker for metastatic papillary thyroid microcarcinoma

Figure 1

Immunohistochemical analysis of EpEx and Ep-ICD expression in papillary thyroid microcarcinoma. The representative photomicrographs show immunostaining of EpEx and Ep-ICD in PTMC. Strong membranous EpEx immunostaining was observed in the non-metastatic group (A), whereas decreased staining of membranous EpEx was observed in aggressive PTMC cases (B). The non-metastatic PTMC show predominant cytoplasmic localization of Ep-ICD and no detectable nuclear Ep-ICD staining (C), while the aggressive cases show nuclear and strong cytoplasmic Ep-ICD accumulation (D). (E) depicts the negative control. Original magnification x 400.

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BMC Cancer

ISSN: 1471-2407

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