Table 3 Genes differentially expressed in GC specimens with higher levels of Snail expression

Genes upregulated in specimens with higher levels (≥75%) of Snail expression (P< 0.05)

ILMN_2374449

SPP1

Secreted phosphoprotein 1

ILMN_2337923

TPD52L1

Tumor protein D52-like 1

ILMN_1679838

WBP5

WW domain binding protein 5

ILMN_2078592

C6orf105

Androgen-dependent TFPI-regulating protein

ILMN_1714383

TPD52L1

Tumor protein D52-like 1

ILMN_1674817

C1orf115

Chromosome 1 open reading frame 115

ILMN_1813561

SCIN

Scinderin

ILMN_1759818

SORL1

Sortilin-related receptor, L(DLR class) A repeats containing

ILMN_1745686

MFHAS1

Malignant fibrous histiocytoma amplified sequence 1

ILMN_2060115

SORL1

Sortilin-related receptor, L(DLR class) A repeats containing

ILMN_2337263

PKIB

Protein kinase (cAMP-dependent, catalytic) inhibitor beta

ILMN_2173835

FTHL3

Ferritin, heavy polypeptide 1 pseudogene 3

ILMN_1791057

IFNAR2

Interferon (alpha, beta and omega) receptor 2

ILMN_1807114

LOC255620

Similar to unc-93 homolog B1 (C. elegans), transcript variant 1 (LOC255620), mRNA

ILMN_1669393

GGT1

Gamma-glutamyltransferase 1

ILMN_1685798

MAGEA6

Melanoma antigen family A, 6

ILMN_3269395

GGT2

Gamma-glutamyltransferase 2

ILMN_1669833

SH2B2

SH2B adaptor protein 2

ILMN_3238534

LOC100133817

Hypothetical protein LOC100133817

ILMN_2099315

TRPM8

Transient receptor potential cation channel, subfamily M, member 8

ILMN_3298065

LOC729195

Similar to apical early endosomal glycoprotein

ILMN_1717726

FLJ43752

Long intergenic non-protein coding RNA 336

ILMN_1670452

ANKRD20A1

Ankyrin repeat domain 20 family, member A1

ILMN_3201060

LOC100132655

Hypothetical protein LOC100132655

ILMN_3282829

LOC727913

Similar to iduronate 2-sulfatase (Hunter syndrome)

ILMN_2339691

SYVN1

Synovial apoptosis inhibitor 1, synoviolin

ILMN_1785549

SLC30A2

Solute carrier family 30 (zinc transporter), member 2

ILMN_3191898

LOC100129630

Hypothetical LOC100129630

ILMN_1704204

LOC642204

Ankyrin repeat domain-containing protein 26-like

ILMN_1682280

LOC647753

Hypothetical protein LOC647753

ILMN_3201944

LOC646438

Hypothetical LOC646438

ILMN_2233314

SPANXA1

Sperm protein associated with the nucleus, X-linked, family member A1

ILMN_3305980

NS3BP

NS3BP

ILMN_1747850

CRIM2

Kielin/chordin-like protein

ILMN_1700590

LOC645590

Similar to cAMP-dependent protein kinase type I-beta regulatory subunit

ILMN_1766316

FLJ32679

Golgin-like hypothetical protein LOC440321

ILMN_1890741

Hs.552561

Pancreatic islet cDNA clone hbt09690 3, mRNA sequence

ILMN_3308255

MIR33A

MicroRNA 33a

ILMN_1815716

LMLN

Leishmanolysin-like (metallopeptidase M8 family)

ILMN_1654945

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

ILMN_2256050

SERPINA1

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

ILMN_1759487

EGFLAM

EGF-like, fibronectin type III and laminin G domains

ILMN_1760410

LOC653086

Similar to RAN-binding protein 2-like 1 isoform 2

ILMN_1668969

MIXL1

Mix paired-like homeobox

ILMN_3279757

LOC100132532

Hypothetical protein LOC100132532

ILMN_1715372

CAMKK1

Calcium/calmodulin-dependent protein kinase kinase 1, alpha

ILMN_1731370

C9orf84

Chromosome 9 open reading frame 84

ILMN_1679049

COLEC12

Collectin sub-family member 12

ILMN_1676011

LOC642561

Similar to FXYD domain-containing ion transport regulator 6

ILMN_1815442

LOC652875

Similar to Protein KIAA0685

ILMN_1737213

LOC653641

Golgin A6 family, member C

ILMN_1793529

LOC389031

Myosin

ILMN_1709319

C13orf39

Methyltransferase like 21C

ILMN_2284930

FLJ40296

Proline rich 20A

ILMN_1678310

TXNRD3IT1

Thioredoxinreductase 3 neighbor

ILMN_1806052

UNC119

unc-119 homolog (C. elegans)

ILMN_2242345

LPAL2

Lipoprotein, Lp(a)-like 2, pseudogene

ILMN_1687725

C17orf41

ATPase family, AAA domain containing 5

ILMN_1886395

Hs.574341

Soares_multiple_sclerosis_2NbHMSP Homo sapienscDNA clone IMAGp998G11618; IMAGE:126826, mRNA sequence

ILMN_3308612

MIR149

MicroRNA 149

ILMN_1811103

PCDHGB5

Protocadherin gamma subfamily B, 5

ILMN_1736104

LOC645218

Hypothetical LOC645218

ILMN_1824307

Hs.571901

Full-length cDNA clone CS0DF20YK03 of Fetal brain of Homo sapiens

ILMN_1803871

RHO

Rhodopsin

ILMN_3237314

LOC732402

Similar to butyrate-induced transcript 1

ILMN_1714191

LOC652682

Similar to Y46G5A.1a

ILMN_3246580

LOC730429

e3 ubiquitin-protein ligase UBR5-like

ILMN_3229028

LOC728586

hCG1981531

ILMN_3239734

LOC100134822

Uncharacterized LOC100134822

ILMN_1769785

SH3MD4

SH3 domain containing ring finger 3

ILMN_3309864

MIR449B

MicroRNA 449b

ILMN_1653927

SNORD83A

small nucleolar RNA, C/D box 83A

ILMN_3200648

LOC151174

uncharacterized LOC151174

ILMN_1652023

AGFG2

ArfGAP with FG repeats 2

ILMN_1749776

LOC642816

Similar to hypothetical protein LOC284701

ILMN_1671985

LOC646829

Hypothetical protein LOC646829

ILMN_1684499

LOC650373

Similar to deubiquitinating enzyme 3

ILMN_1676452

ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

ILMN_1723855

LOC390427

Similar to TBP-associated factor 15 isoform 1

ILMN_1658019

LOC648447

Hypothetical protein LOC648447

ILMN_3227291

LOC728701

Hypothetical LOC728701

ILMN_1767469

LOC650781

Hypothetical protein LOC650781

Genes downregulated in specimens with higher levels (≥75%) of Snail expression (P< 0.05)

ILMN_1796946

ALLC

Allantoicase

ILMN_3248008

LOC442308

Tubulin, beta class I pseudogene

ILMN_3230623

FLJ40039

Uncharacterized LOC647662

ILMN_1676596

LOC642263

Hypothetical LOC642263

ILMN_3165745

ERCC-00084

Synthetic construct clone NISTag41 external RNA control sequence

ILMN_3242420

HCG8

HLA complex group 8

ILMN_1783827

LOC649397

Similar to Tripartite motif protein 44 (DIPB protein) (Mc7 protein)

ILMN_3244733

LOC100131898

Hypothetical protein LOC100131898

ILMN_3195376

LOC100130092

Similar to MAPRE1 protein

ILMN_2123683

FLJ43763

Uncharacterized LOC642316

ILMN_1730601

FAM194A

Family with sequence similarity 194, member A

ILMN_1652015

LOC647451

Similar to heat shock protein 90Bf

ILMN_1784349

LOC647191

Similar to Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein)

ILMN_3251375

WBP11P1

WW domain binding protein 11 pseudogene 1

ILMN_1911713

Hs.550068

UI-E-EJ1-ajn-i-16-0-UI.s1 UI-E-EJ1 Homo sapienscDNA clone UI-E-EJ1-ajn-i-16-0-UI.3, mRNA sequence

ILMN_1888057

Hs.554470

nc63e05.r1 NCI_CGAP_Pr1 Homo sapienscDNA clone IMAGE:745952, mRNA sequence

ILMN_3229818

LOC729828

Misc_RNA (LOC729828), miscRNA

ILMN_1654987

HCG2P7

HLA complex group 2 pseudogene 7

ILMN_1683453

FRAS1

Fraser syndrome 1

ILMN_1840493

Hs.112932

ag03b01.s1 Soares_testis_NHTHomo sapienscDNA clone IMAGE:1056169 3, mRNA sequence

ILMN_1860820

Hs.126468

tm27h01.x1 Soares_NFL_T_GBC_S1 Homo sapienscDNA clone IMAGE:2157841 3, mRNA sequence

ILMN_3227213

LOC728940

Hypothetical LOC728940

ILMN_3247774

LOC100134235

Similar to hCG1642820

ILMN_1902571

Hs.557622

tw46h08.x1 NCI_CGAP_Ut1 Homo sapienscDNA clone IMAGE:2262783 3 similar to contains PTR5.b2 PTR5 repetitive element, mRNA sequence

ILMN_2384405

RTBDN

Retbindin

ILMN_3234879

LOC653786

Otoancorinpseudogene

ILMN_1914891

Hs.334272

RST40254 Athersys RAGE Library Homo sapienscDNA, mRNA sequence

ILMN_3272356

LOC100129315

Hypothetical protein LOC100129315 (LOC100129315), mRNA

ILMN_3230388

LOC100130855

Hypothetical protein LOC100130855( LOC100130855), mRNA

ILMN_1656553

LOC653160

Hypothetical protein LOC653160, transcript variant (LOC653160), mRNA

ILMN_1700935

HAS2

Hyaluronan synthase 2

ILMN_1733783

LOC652790

Similar to anaphase promoting complex subunit 1

ILMN_2209221

DMRT1

Doublesex and mab-3 related transcription factor 1

ILMN_1815118

ZNF554

Zinc finger protein 554

ILMN_3293210

LOC100131031

Similar to hCG2041190 (LOC100131031), mRNA

ILMN_1703222

FRS2

Fibroblast growth factor receptor substrate 2

ILMN_1732807

GPRC6A

G protein-coupled receptor, family C, group 6, member A

ILMN_1875332

Hs.545527

he15g04.x1 NCI_CML1 Homo sapienscDNA clone IMAGE:2919216 3 similar to contains element PTR5 repetitive element

ILMN_3235789

BPY2C

Basic charge, Y-linked, 2C

ILMN_3203116

LOC100131961

Misc_RNA (LOC100131961), miscRNA

ILMN_2198802

FAM22G

Family with sequence similarity 22, member G

ILMN_1858700

Hs.538558

zh20c06.s1 Soares_pineal_gland_N3HPG Homo sapienscDNA clone IMAGE:412618 3, mRNA sequence

ILMN_1873107

Hs.282800

AV649053 GLC Homo sapienscDNA clone GLCBPH07 3, mRNA sequence

ILMN_1891673

Hs.164254

hb73c02.x1 NCI_CGAP_Ut2 Homo sapienscDNA clone IMAGE:2888834 3, mRNA sequence

ILMN_3206632

LOC643802

u3 small nucleolarribonucleoprotein protein MPP10-like

ILMN_1883034

Hs.546089

RST29145 Athersys RAGE Library Homo sapienscDNA, mRNA sequence

ILMN_2373335

LIG3

Ligase III, DNA, ATP-dependent

ILMN_3239639

CD200R1L

CD200 receptor 1-like

ILMN_1870857

Hs.148168

Barstead spleen HPLRB2 Homo sapienscDNA clone IMAGp998L113601 ; IMAGE:1425178, mRNA sequence

ILMN_1813909

CRSP2

Mediator complex subunit 14

ILMN_1891885

Hs.332843

qg83a07.x1 Soares_NFL-T_GBC_S1 Homo sapienscDNA clone IMAGE:1841748, mRNA sequence

ILMN_3235126

LOC100133558

Similar to hCG1642170

ILMN_1677186

MGC52498

Family with sequence similarity 159, member A

ILMN_3252608

HCRP1

Hepatocellular carcinoma-related HCRP1

ILMN_1652871

PLSCR5

Phospholipid scramblase family, member 5

ILMN_1698894

OR5AS1

Olfactory receptor, family 5, subfamily AS, member 1

ILMN_1705828

RICTOR

RPTOR independent companion of MTOR, complex 2

ILMN_1683046

OR6Y1

Olfactory receptor, family 6, subfamily Y, member 1

ILMN_2114812

ONECUT1

One cut homeobox 1

ILMN_1770248

PDLIM2

PDZ and LIM domain 2 (mystique)

ILMN_1784272

CD1E

CD1e molecule

ILMN_1755635

FLJ33534

Hypothetical protein FLJ33534 (FLJ33534), mRNA

ILMN_1799067

TRY1

Protease, serine, 1 (trypsin 1)

ILMN_1693448

LOC643811

Similar to FERM domain containing 6

ILMN_1723323

HCG4

HLA complex group 4 (non-protein coding)

ILMN_1865604

Hs.253267

60270330F1 NCI_CGAP_Skn3 Homo sapienscDNA clone IMAGE:4800534 5, mRNA sequence

ILMN_3308698

MIR1276

MicroRNA 1276

ILMN_1714014

LOC644491

NMDA receptor regulated 2 pseudogene

ILMN_2114185

C1orf104

RUSC1 antisense RNA 1 (non-protein coding)

ILMN_1911044

Hs.540915

nf66b06.s1 NCI_CGAP_Co3 Homo sapienscDNA clone IMAGE:924851 3, mRNA sequence

ILMN_1748543

STRC

Stereocilin

ILMN_1675221

DGKZ

Diacylglycerol kinase, zeta

ILMN_1726263

LOC653748

Similar to dipeptidylaminopeptidase-like protein 6 (dipeptidylpeptidase VI) (dipeptidylpeptidase 6) (dipeptidyl peptidase VI-like protein) (dipeptidylaminopeptidase-related protein) (DPPX)

ILMN_1817113

Hs.547985

UI-H-BI0p-abm-h-10-0-UI.s1 NCI_CGAP_Sub2 Homo sapienscDNA clone IMAGE:2712450 3, mRNA sequence

ILMN_1793525

KIR2DS3

Killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3

ILMN_2415617

C10orf72

V-set and transmembrane domain containing 4

ILMN_1746277

MLLT4

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

ILMN_1678246

LOC644001

Hypothetical protein LOC644001

ILMN_3257856

LOC100130938

Hypothetical LOC100130938 (LOC100130938), mRNA

ILMN_1865630

Hs.116333

Soares_testis_NHTHomo sapienscDNA clone IMAGp998A031828, mRNA sequence

ILMN_2152028

LOC642452

Hypothetical LOC642452 (LOC642452), mRNA

ILMN_3244579

LOC649330

Heterogeneous nuclear ribonucleoprotein C-like

ILMN_1905832

Hs.564127

UI-E-DW1-ahc-g-05-0-UI.r1 UI-E-DW1 Homo sapienscDNA clone UI-E-DW1-ahc-g-05-0-UI.5, mRNA sequence

ILMN_1897251

Hs.547715

UI-E-EJ0-ahv-e-11-0-UI.s1 UI-E-EJ0 Homo sapienscDNA clone UI-E-EJ0-ahv-e-11-0-UI 3, mRNA sequence

ILMN_1782800

LOC651410

Hypothetical protein LOC651410

ILMN_1732554

ZNF346

Zinc finger protein 346

ILMN_1674014

LOC653878

Similar to Cytosolic acyl coenzyme A thioester hydrolase, inducible (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I) (CTE-Ib)

ILMN_1911501

Hs.543905

xi89f08.x1 NCI_CGAP_Mel3 Homo sapienscDNA clone IMAGE:265999 3, mRNA sequence

ILMN_1878305

Hs.262789

xk07d09.x1 NCI_CGAP_Co20 Homo sapienscDNA clone IMAGE:2666033 3, mRNA sequence

ILMN_1858245

Hs.156566

Soares_testis_NHTHomo sapienscDNA clone IMAGp998M073519, mRNA sequence

ILMN_1704313

GSTCD

Glutathione S-transferase, C-terminal domain containing

ILMN_1707398

ESRRB

Estrogen-related receptor beta

ILMN_3307954

L3MBTL4

l(3)mbt-like 4 (Drosophila)

ILMN_1851244

Hs.59368

UI_H_BI1_aex-h-12-0-UI.s1 NCI_CGAP_Sub3 Homo sapienscDNA clone IMAGE:2720903 3, mRNA

ILMN_1828556

Hs.541581

nac23e12.x1 Lupski_sciatic_nerveHomo sapienscDNA clone IMAGE:3394270 3, mRNA sequence

ILMN_1692894

LOC654042

Similar to dehydrogenase/reductase (SDR family) member 4 like 2

ILMN_1893728

Hs.377660

Homo sapienscDNA FLJ26242 fis, clone DMC00770

ILMN_1667005

LOC652676

Similar to similar to hypothetical protein FLJ36144

ILMN_3241607

LOC100132106

Hypothetical LOC100132106

ILMN_1797503

GOLGA8G

Golgin A8 family, member G

ILMN_1828034

Hs.154513

ik89c11.z1 Human insulinomaHomo sapienscDNA clone IMAGE:6027645 3, mRNA sequence

ILMN_1886816

Hs.544491

qq31a07.x1 Soraes_NhHMPu_S1 Homo sapienscDNA clone IMAGE:1934100 3, mRNA sequence

ILMN_1847950

Hs.505398

wq87c02.x1 NCI_CGAP_GC6 Homo sapienscDNA clone IMAGE:2479010 3, mRNA sequence

ILMN_1734479

ACCN3

Acid-sensing (proton-gated) ion channel 3

ILMN_1675025

H2BFM

H2B histone family, member M

ILMN_2073279

SIM1

Single-minded homolog 1 (Drosophila)

ILMN_1910185

Hs.98563

zw57h03.s1 Soares_total_fetus_Nb2HF8_9w Homo sapienscDNA clone IMAGE:774197 3, mRNA sequence

ILMN_3251491

UQCRB

Ubiquinol-cytochrome c reductase binding protein

ILMN_2180315

ATG4D

ATG4 autophagy related 4 homolog D (S. cerevisiae)

ILMN_1885583

Hs.542934

Homo sapienscDNA FLJ26431 fis, clone KDN01390

ILMN_1743301

MSR1

Macrophage scavenger receptor 1

ILMN_1809820

LOC648963

Similar to retinitis pigmentosa 1-like 1

ILMN_1869348

Hs.460114

UI-E-EJ0-ahv-d-07-0-UI.s1 UI-E-EJ0 Homo sapienscDNA clone UI-E-EJ0-ahv-d-07-0-UI 3, mRNA sequence

ILMN_1711332

TFEC

Transcription factor EC

ILMN_2228538

IRAK1BP1

Interleukin-1 receptor-associated kinase 1 binding protein 1

ILMN_1756455

IL5RA

Interleukin 5 receptor, alpha

ILMN_1719202

ZNF174

Zinc finger protein 174

ILMN_1847029

Hs.553290

HESC3_84_D06.g1_A036 Human embryonic stem cells Homo sapienscDNA clone IMAGE:7483454 5, mRNA sequence

ILMN_1740217

HACE1

HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

ILMN_1787464

LOC651296

Similar to RAB, member of RAS oncogene family-like 2B isoform 1

ILMN_1734096

DCLRE1A

DNA cross-link repair 1A

ILMN_2391333

CYP20A1

Cytochrome P450, family 20, subfamily A, polypeptide 1

ILMN_2226314

DBR1

Debranching enzyme homolog 1 (S. cerevisiae)

ILMN_2379560

CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

ILMN_2078466

DZIP1L

DAZ interacting protein 1-like

ILMN_1653039

LOC642934

Hypothetical protein LOC642934 (LOC642934), mRNA

ILMN_2044293

KBTBD7

Kelch repeat and BTB (POZ) domain containing 7

ILMN_1809951

ZNF200

Zinc finger protein 200

ILMN_1760280

NXT1

NTF2-like export factor 1

ILMN_1657796

STMN1

Stathmin 1

ILMN_1793578

ZFP37

Zinc finger protein 37 homolog (mouse)