Table 1 SEREX-defined genes identified by autologous screening of C-164 cDNA library
From: Serological identification of Tektin5 as a cancer/testis antigen and its immunogenicity
Antigen | No. of clones | Identity/similarities | DNA microarray (fold change)1 | ||
|---|---|---|---|---|---|
C-164 | C-1 | C-29 | |||
OY-CO-1 | 1 | Lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP) | 0.72 | 0.60 | 0.46 |
OY-CO-2 | 1 | Rho GTPase-activating protein 18(ARHGAP18) | 4.57 | 1.44 | 1.50 |
OY-CO-3 | 10 | Dihydrolipoamide dehydrogenase (DLD) | 1.27 | 0.55 | 0.30 |
OY-CO-4 | 1 | Adenomatous polyposis coli (APC), transcript variant 3 | 3.61 | 0.74 | 3.22 |
OY-CO-5 | 1 | MRE11 meiotic recombination 11 homolog A (MRE11A), transcript variant 1 | 2.66 | 9.02 | 3.72 |
OY-CO-6 | 1 | Heat shock protein 90 kDa beta (Grp94), member 1 (HSP90B1) | 1.02 | 2.75 | 1.25 |
OY-CO-7 | 1 | Transcription elongation factor B (SII), polypeptide 2 (18 kDa, elongin B) (TCEB2), transcript variant 1 | 1.52 | 2.74 | 1.48 |
OY-CO-8 | 1 | Wilms tumor 1-associated protein (WTAP), transcript variant 2 | 1.06 | 0.35 | 0.42 |
OY-CO-9 | 1 | Ribosomal protein L35a (RPL35A) | 1.77 | 1.95 | 2.31 |
OY-CO-10 | 1 | Polyglutamine-binding protein 1 (PQBP1), transcript variant 7 | 1.26 | 1.27 | 1.30 |
OY-CO-11 | 2 | PRP38 pre-mRNA processing factor 38 (yeast) domain containing B (PRPF38B), transcript variant 1 | 3.03 | 2.88 | 2.51 |
OY-CO-12 | 2 | Coatomer protein complex, subunit alpha (COPA), transcript variant 2 | 1.26 | 0.73 | 0.75 |
OY-CO-13 | 1 | Keratin 18 (KRT18), transcript variant 1 | 1.46 | 1.24 | 0.66 |
OY-CO-14 | 1 | No strong homology, retrotransposon MSTP055 mRNA | - | - | - |
OY-CO-15 | 1 | Ribosomal protein L13 (RPL13), transcript variant 2 | 0.92 | 0.84 | 1.67 |
OY-CO-16 | 1 | Partial mRNA for KLEIP (kelch-like ECT2 interacting protein), (KLHLX gene) | - | - | - |
OY-CO-17 | 2 | BTB (POZ) domain containing 2 (BTBD2) | 0.79 | 0.84 | 0.83 |
OY-CO-18 | 1 | Nuclear receptor interacting protein 1 (NRIP1) | 0.81 | 0.87 | 0.92 |
OY-CO-19 | 1 | Ribosomal protein L8 (RPL8), transcript variant 2 | 1.01 | 2.63 | 1.69 |
OY-CO-20 | 2 | Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) | 2.92 | 1.00 | 0.59 |
OY-CO-21 | 1 | WD repeat, sterile alpha motif and U-box domain containing 1 (WDSUB1), transcript variant 3 | 1.69 | 1.19 | 0.76 |