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Table 5 Association of exposure to asbestos with nasal malignancies

From: Risk factors for nasal malignancies in German men: the South-German Nasal cancer study

 

Controls (%)

Cases (%)

OR (95% CI)

All study participants

   

Reference*

2105 (87.7)

360 (84.3)

1.0

Ever exposed for at least 1 year§

296 (12.3)

67 (15.7)

0.81 (0.47–1.39)

Per year of exposure§

296 (12.3)

67 (15.7)

1.02 (1.00–1.04)

Exposure (tertiles) < 5 years

92 (3.8)

11 (2.6)

0.55 (0.24–1.24)

5 < 14 years

106 (4.4)

26 (6.1)

1.13 (0.56–2.28)

14+ years

98 (4.1)

30 (7.0)

1.34 (0.32–5.59)

Smokers

   

Reference*

1237 (87.4)

246 (84.5)

1.0

Ever exposed for at least 1 year§

178 (12.6)

46 (15.8)

1.23 (0.74–1.91)

Per year of exposure§

178 (12.6)

46 (15.8)

1.03 (1.01–1.06)

Exposure (tertiles) < 5 years

58 (4.1)

8 (2.7)

0.75 (0.31–1.84)

5 < 14 years

66 (4.7)

14 (4.8)

0.93 (0.48–1.84)

14+ years

54 (3.8)

24 (8.2)

2.30 (1.17–4.53)

Never-smokers

   

Reference*

868 (88.0)

114 (84.4)

1.0

Ever exposed for at least 1 year§

118 (12.0)

21 (15.6)

0.41 (0.08–2.03)

Per year of exposure§

118 (12.0)

21 (15.6)

1.17 (0.42–3.28)

Exposure (tertiles) < 5 years

34 (3.4)

3 (2.2)

0.59 (0.15–2.28)

5 < 14 years

40 (4.1)

12 (8.9)

1.17 (0.42–3.28)

14+ years

44 (4.5)

6 (4.4)

0.60 (0.15–2.29)

  1. * never exposed to asbestos.
  2. §daily/several days per week.
  3. Adjustments: Year of birth, community size, educational attainment, pack-years (all study participants), snuff package-years, years of exposure to hardwood dust, organic solvents, use of nasal spray/nasal lavage and ever-use of insecticides in residences.