Table 6 Diagnostic accuracy of cytology, DNA integrity index and mesothelin
| Â | All malignant pleural effusions | Sensitivity (%) | Sensitivity (%) | Malignant pleural mesothelioma only | Sensitivity (%) | Sensitivity (%) |
|---|---|---|---|---|---|---|
| Â | Area under curve (95% CI) | Â | Â | Area under curve (95% CI) | Â | Â |
Cytology | Â | 51 | 100 | Â | 31 | 100 |
DNA Integrity index cut-off: 1.02 | 0.766 (0.646 - 0.866) | 57 | 90 | 0.823 (0.676-0.970) | 75 | 90 |
Pleural fluid mesothelin cut-off: 12.72 nM | 0.620 (0.480-0.759) | 37 | 90 | 0.885 (0.774-0.997) | 75 | 90 |
Serum mesothelin Cut-off: 1.34 nM | 0.674 (0.546-0.802) | 44 | 90 | 0.941 (0.869-1.00) | 75 | 90 |