Figure 1From: SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors Sanger sequencing validated a nonsense SDHA exon 2 p.Arg31X mutation in both tumor and normal DNA. The SDHA sequence electropherogram of the tumor DNA contained predominantly the mutated allele (T), indicating relative loss of the wild-type SDHA allele, compared to the normal DNA.Back to article page