Figure 2From: HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast Relative expression of PDK1, PGK1, VEGF (well-known HIF-1 target genes) and S14 (housekeeping gene) checked by semi-quantitative PCR analysis in MCF7 cell monolayers under normoxic conditions (Monolayer Normoxia); MCF7 3-D spheroids (Spheroids); and MCF7 cell monolayers under hypoxic conditions (Monolayer Hypoxia). The figure is representative of three similar experiments.Back to article page