Table 1 Association between different patient and cancer-specific variables with the pre-operative CRP value
From: Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients
Variable | CRP <4 mg/l | CRP 4–10 mg/l | CRP >10 mg/l | p-value | Test |
|---|---|---|---|---|---|
Age, mean (95% CI) | 60.9 (59.9 - 61.9) | 62.1 (60.4 - 63.8) | 63.4 (62.4 - 64.5) | 0.005 | ANOVA |
Sex | 0.28 | chi-square | |||
female | 225 (36.5%) | 51 (31.3%) | 124 (32.5%) | ||
male | 391 (63.5%) | 112 (68.7%) | 258 (67.5) | ||
Side | 0.81 | chi-square | |||
right | 325 (52.8%) | 86 (52.8%) | 193 (50.5%) | ||
left | 286 (46.5%) | 77 (47.2%) | 187 (49.0%) | ||
bilateral | 4 (0.7%) | 0 | 2 (0.5%) | ||
Type of surgery | <0.001 | chi-square | |||
Radical nephrectomy | 408 (66.2%) | 130 (79.8%) | 342 (89.8%) | ||
Partial nephrectomy | 208 (33.8%) | 33 (20.2%) | 39 (10.2%) | ||
Stage | <0.001 | chi-square | |||
pT1a | 284 (46.6%) | 58 (35.8%) | 39 (10.4%) | ||
pT1b | 164 (26.9%) | 40 (24.7%) | 55 (14.7%) | ||
pT2 | 44 (7.2%) | 15 (9.3%) | 44 (11.7%) | ||
pT3a | 66 (10.8%) | 23 (14.2%) | 78 (20.8%) | ||
pT3b/c | 49 (8.2%) | 26 (16.0%) | 142 (37.9%) | ||
pT4 | 2 (0.3%) | 0 | 17 (4.5%) | ||
LN metastasis1 | 13 (2.1%) | 5 (3.1%) | 62 (16.4%) | <0.001 | chi-square |
Pulmonal/visceral metastasis1 | 18 (2.9%) | 14 (8.6%) | 114 (30.0%) | <0.001 | chi-square |
Grade | <0.001 | chi-square | |||
G1 | 144 (23.8%) | 30 (18.9%) | 26 (7.0%) | ||
G2 | 416 (68.8%) | 110 (69.2%) | 212 (56.7%) | ||
G3 | 45 (7.4%) | 18 (11.3%) | 127 (34.0%) | ||
G4 | 0 | 1 (0.6%) | 9 (2.4%) | ||
Histological subtype | 0.08 | chi-square | |||
non ccRCC | 86 (14.3%) | 24 (14.9%) | 36 (9.7%) | ||
ccRCC | 516 (85.7%) | 137 (85.1%) | 336 (90.2%) |