Table 6 Comparison of Diagnostic Results of NAB alone and NAB combined with Tumor Markers according to histological subtype
Diagnostic Method | Sensitivity(%) | Specificity(%) | Accuracy(%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|
Adencarcinoma subtype (n=92) | |||||
NAB alone | 79.3 | 100 | 87.1 | 100 | 74.3 |
NAB+Serum Tumor marker | |||||
CYFRA (3.3) | 81.5 | 81.8 | 81.6 | 88.2 | 72.6 |
CEA (5) | 81.5 | 90.9 | 85 | 93.8 | 74.6 |
SCC (2) | 79.3 | 92.7 | 84.4 | 94.8 | 72.9 |
NAB+Cytological Tumor marker | |||||
CYFRA (15.7) | 92.4 | 98.2 | 94.6 | 98.8 | 88.5 |
CEA (0.6) | 89.1 | 92.7 | 90.5 | 95.3 | 83.6 |
SCC (0.86) | 83.5 | 70.9 | 81.6 | 88 | 78 |
Squamous cell carcinoma subtype (n=29) | |||||
NAB alone | 89.7 | 100 | 96.4 | 100 | 94.8 |
NAB+Serum Tumor marker | |||||
CYFRA (3.3) | 93.1 | 81.8 | 85.7 | 73 | 95.7 |
CEA (5) | 93.1 | 90.9 | 91.7 | 84.4 | 96.2 |
SCC (2) | 93.1 | 92.7 | 92.9 | 87.1 | 96.2 |
NAB+Cytological Tumor marker | |||||
CYFRA (15.7) | 100 | 98.2 | 98.8 | 96.7 | 100 |
CEA (0.6) | 96.6 | 92.7 | 94 | 87.5 | 98.1 |
SCC (0.86) | 100 | 70.9 | 81 | 64.4 | 100 |