Table 2 Comparisons of physical and psychosocial symptom burden between chemotherapy lines.
From: Quality of life across chemotherapy lines in patients with cancers of the pancreas and biliary tract
EORTC QLQ-C30 | (0) | (1) | (2) | (3) | p |
|---|---|---|---|---|---|
| Â | Adjuvant CT | 1st pall. CT | 2nd pall. CT | 3rd+pall. CT | Â |
Physical Functioning | 73.52,3 | 71.02 | 65.60,1 | 62.80 | 0.036 |
Role Functioning | 58.0 | 58.4 | 53.1 | 53.1 | 0.438 |
Social Functioning | 79.0 | 74.4 | 74.8 | 69.6 | 0.145 |
Emotional Functioning | 84.41,2,3 | 73.80 | 71.70 | 71.10 | <0.001 |
Cognitive Functioning | 92.01,2 | 86.90 | 85.10 | 89.5 | 0.034 |
Global QOL | 60.62 | 59.72 | 51.701 | 53.9 | 0.002 |
Fatigue | 39.12,3 | 41.52,3 | 50.00,1 | 53.10,1 | 0.004 |
Pain | 14.11,2,3 | 21.80,2 | 28.80,1 | 23.60 | <0.001 |
Nausea/Vomiting | 7.6 | 13.2 | 12.2 | 11.0 | 0.128 |
Dyspnoea | 10.82,3 | 14.52,3 | 23.60,1,3 | 31.40,1,2 | <0.001 |
Appetite Loss | 25.6 | 28.6 | 32.8 | 38.8 | 0.194 |
Sleeping Disturbances | 18.71,2,3 | 32.50 | 31.30 | 29.20 | 0.001 |
Constipation | 19.4 | 17.9 | 12.0 | 14.3 | 0.173 |
Diarrhoea | 7.52,3 | 12.53 | 16.60 | 21.30,1 | 0.002 |
Financial Impact | 10.8 | 11.3 | 12.0 | 12.8 | 0.946 |
Taste Alterations | 12.72,3 | 17.8 | 22.00 | 22.60 | 0.046 |