Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors

Table 2 High level amplifications and homozygous deletions in different cell lines

CNAs	Region^a	Cell line	Start	Stop	Genes
HLA	7p11	KYSE30, KYSE450	54572103	57613746	VSTM2A, SEC61G, EGFR, LANCL2, VOPP1, FKBP9L, ZNF713, MRPS17, GBAS, PSPH, CCT6A, SUMF2, PHKG1, CHCHD2, ZNF479, ZNF716
	8q24.21	KYSE450, KYSE510	128548643	129216964	POU5F1B, LOC727677, MYC, PVT1
	11q13.3-q13.4	KYSE30, KYSE180, KYSE510	68232360	70964483	MTL5, CPT1A, MRPL21, IGHMBP2, MRGPRD, MRGPRT, TPCN2, MYEOV, CCND1, ORAOV1, FGF19, FGF4, FGF3, ANO1, FADD, PPFIA1, CTTN, SHANK2, DHCR7, NADSYN1, KRTAP5-7, KRTAP5-8, KRTAP5-9, KRTAP5-10, KRTAP5-11
HD	9p21.3	KYSE180, KYSE450, KYSE510, YES2	21958099	22136626	CDKN2A, CDKN2B, CDKN2B-AS1

HLA: high level amplification; HD: homozygous deletion; the Start and Stop positions are annotated by hg18.
^a Regions of amplifications or deletions in at least two cell lines.

ISSN: 1471-2407