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Table 4 ALDH1A1 immunohistochemical staining according to diagnosis and histological characteristics of the epithelial and stromal components of ovarian samples

From: Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures

Characteristics

n a

epithelial

stromal

 
  

score b

P c

C.I. d

score b

P c

C.I.d

Diagnosis

       

healthy

5

0.15 ± 0.22

0.102

 

0.60 ± 0.82

0.08

 

benign

4

1.94 ± 2.96

  

4.44 ± 3.14

  

borderline

8

3.78 ± 3.37

  

1.94 ± 1.92

  

invasive

101

1.66 ± 2.71

  

1.85 ± 2.25

  

Histology

       

serous

40

0.67 ± 1.52

< 0.001*

(-0.8, 1.5)

1.12 ± 1.28

0.02

(-3.1, -0.5)**

mucinous

12

5.65 ± 3.05

 

(3.7, 7.0)**

1.98 ± 2.17

 

(-2.7, 0.9)

endometrioid

19

3.38 ± 3.28

 

(1.6, 4.5)**

1.76 ± 2.70

 

(-2.7, 0.4)

clear cell

29

0.31 ± 0.45

 

reference

2.90 ± 2.74

 

reference

  1. a Number of cases.
  2. b Immunohistochemistry staining score expressed as mean ± SD.
  3. c P-value, ANOVA test of equal means among the four groups (* equal population variances assumption did not meet, corresponding p-value using Kruskal-Wallis test for equal medians was displayed).
  4. d Two-sided 95% confidence interval (C.I.) for the difference in means, Dunnett’s post-hoc test compared to value in healthy (in Diagnosis group) or clear cell (in Histology group) as the “reference” group. Dunnett’s test was performed only when the ANOVA or Kruskal-Wallis result was significant (p < 0.05).
  5. ** Significant based on Dunnett’s test (family error rate set to 0.05).
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BMC Cancer

ISSN: 1471-2407

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