Figure 2
From: Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma
Overexpression of fascin leads to increase in cell migration, invasion and MMPs activity. (A and B) Phase contrast images (magnification 10×) of wound closure at 0 h, 6 h and 12 h of the vector control (AW-GFP-Cont) and fascin overexpressed clones (AW-Fascin-1 and AW-Fascin-2) are shown in the figure. Scale bar: 100 μm. The data shown is the average migration rate from three independent experiments with the mean and standard deviation (p < 0.05). (C) Boyden chamber invasion assay of vector control (AW-GFP-Cont) and fascin overexpressed clones (AW-Fascin-1 and AW-Fascin-2). The data shown is the average from three independent experiments with the mean and standard deviation (p < 0.01). (D) Zymogram showing MMP-2 activity in vector control (AWGFP-Cont) and fascin overexpressed (AW-Fascin-1 and AW-Fascin-2) cells.