Skip to main content
Figure 5 | BMC Cancer

Figure 5

From: Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

Figure 5

Overexpression of TG2 in MEF tg2-/- enhances cell migration. The ability of TG2 and m-TG2 to induce cell migration was tested in response to db-cAMP (100 μM) stimulation in the presence of PKA inhibitor H89 (100 nM) and Akt inhibitor MK-2206 (20 nM). The data represent the mean ± SEM for n = 9; * P < 0.05 (TG2 vs. vector control); # P < 0.05 (m-TG2 vs. TG2); @ P < 0.05 (TG2 vs. Akt inhibitor).

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us