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Table 2 The mRNA levels of IGF-1, IGF-1R, IGF-2, IGF-2R, IGFBP-3, ERα and ERβ in EAC, tumor-adjacent, and control groups

From: Insulin-like growth factors in endometrioid adenocarcinoma: Correlation with clinico-pathological features and estrogen receptor expression

groups

n

IGF-1

IGF-1R

IGF-2

IGF-2R

IGFBP-3

ERα

ERβ

Control

42

0.58 ± 0.30

0.54 ± 0.32

0.33 ± 0.19

0.04 ± 0.03

4.58 ± 3.35

16.24 ± 10.10

50.10 ± 21.60

EAC

58

1.19 ± 00.79*

6.23 ± 3.98*

2.44 ± 2.32*

4.32 ± 2.98*

14.47 ± 12.31*

10.67 ± 7.63

31.44 ± 25.22

Tumor-adjacent

31

2.66 ± 01.73#

35.34 ± 22.02#

8.59 ± 7.13#

0.39 ± 0.36#

8.28 ± 4.57#

45.54 ± 33.58#

529.62 ± 269.7#

  1. *p < 0.05 vs control,#P < 0.05 vs EAC (endometrioid adenocarcinoma) by one-way ANOVA.
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BMC Cancer

ISSN: 1471-2407

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