Figure 5From: Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition CTC detection targeting human gene transcripts. Representation of tumour growth in xenografted mice. CTCs were detectable at a tumour size of 50 mm2 for all tested cell lines. CTCs out of blood samples were mostly negative for mRNA of EpCAM, MUC-1 and Her2 but showed signals for housekeeping-genes and Vimentin (MDA-MB-231, KPL-4).Back to article page