Table 2 Characteristics of lung cancer cases and controls patients of CAPUA study
From: Genetic polymorphisms in MMP 2, 9 and 3genes modify lung cancer risk and survival
Variable | Cases (n = 879) n (%) | Controls (n = 803) n (%) | P a |
|---|---|---|---|
Gender | |||
Male | 785 (89.3) | 688 (85.7) | |
Female | 94 (10.7) | 115 (14.3) | 0.024 |
Age (yrs), mean (SD) | 66.1 (10.6) | 64.4 (11.2) | 0.002 |
Smoking Status | |||
Never | 53 (6.1) | 231 (29.1) | |
Ever | 821 (93.9) | 563 (70.9) | 0.000 |
Former | 369 (42.3) | 337 (43.0) | |
Current | 449 (51.5) | 215 (27.5) | 0.000 |
Pack-years b, mean (SD) | 62.2 (36.2) | 36.3 (30.8) | 0.000 |
Family history of cancer | |||
No | 486 (58.3) | 473 (60.3) | |
Yes | 347 (41.7) | 311 (39.7) | 0.416 |
Lung cancer | 91 (10.9) | 52 (6.6) | |
Other cancers | 256 (30.7) | 259 (33.0) | 0.009 |
Histological types | |||
Squamous cell carcinoma | 358 (40.7) | ||
Adenocarcinoma | 264 (30.0) | ||
Small cell carcinoma | 150 (17.1) | ||
Non-differentiated | 54 (6.1) | ||
Large cell carcinoma | 24 (2.7) | ||
Others | 15 (1.7) | ||
Clinical diagnosis | 6 (0.7) | ||
Missing | 8 (0.9) | ||
Clinical stages NSCLC | |||
I | 186 (25.9) | ||
II | 58 (8.1) | ||
III | 245 (34.1) | ||
IV | 229 (31.9) | ||
SCLC | |||
LS (Limited stage) | 78 (52.3) | ||
ES (Extend stage) | 71 (47.7) | ||
Calories, mean (SD) | 2405.6 (845.4) | 2276.9 (700.4) | 0.045 |
Alcohol consumption (gr), mean (SD) | 26.4 (39.7) | 22.2 (35.5) | 0.033 |
Occupation (list A) | |||
No | 703 (80.7) | 677 (87.1) | |
Yes | 168 (19.3) | 100 (12.9) | 0.000 |